Purdue Pharmaceutical, the makers of OxyContin, and their owners the Sackler Brothers will pay a nearly $275 million settlement in a lawsuit brought by the State of Oklahoma. Nearly $200 million from the settlement will fund a new addiction treatment and research center at Oklahoma State University.

The suit, brought in 2017 by Oklahoma Attorney General Mike Hunter, accuses Purdue, Johnson & Johnson and Teva Industries of marketing their opioid pain drugs deceptively by downplaying the risks of addiction while overstating their benefits. The settlement only covers Purdue, and claims are still pending against the other two companies, with the trial date still set for May 28.

Oklahoma Attorney General Mike Hunter confirmed the settlement at a press conference held in Tulsa on Tuesday. Hunter said at the conference that he intends to “hold accountable other defendants … for their role in creating the worst public health crisis in our state and nation we’ve ever seen.” He stated that he made extensive efforts to ensure that Purdue could not declare bankruptcy in order to avoid paying the full settlement.

The settlement is by far the largest among settlements paid by pharmaceutical companies in similar suits brought by states. The company settled a lawsuit brought by West Virginia in 2004 for $10 million and one brought by Kentucky in 2015 for $24 million.

Opioids deaths by overdose in the US, both from prescription painkillers such as OxyContin as well as heroin and fentanyl, climbed to 47,600 in 2017, according to the US Centers for Disease Control and Prevention.