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Issued by Drug Enforcement Administration

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Proposed amendment; notice of intent. SUMMARY: The Administrator of the Drug Enforcement Administration is issuing this notice of intent to publish a temporary order to schedule the synthetic opioids, N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)propionamide (ortho-fluorofentanyl or 2-fluorofentanyl), N-(1-phenethylpiperidin-4-yl)-N-phenyltetrahydrofuran-2-carboxamide (tetrahydrofuranyl fentanyl), and 2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide (methoxyacetyl … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of proposed rulemaking. SUMMARY: The Drug Enforcement Administration (DEA) proposes to remove naldemedine (4 R, 4a S, 7a R, 12b S)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-(2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-2-yl)-2,3,4,4a,5,7a-hexahydro-1 H-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide) including its salts from the schedules of the Controlled Substances Act (CSA). This action is pursuant … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of intent. SUMMARY: The Administrator of the Drug Enforcement Administration is issuing this notice of intent to issue a temporary order to schedule the synthetic opioid, N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide (acryl fentanyl or acryloylfentanyl), into Schedule I pursuant to the temporary … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of intent. SUMMARY: The Administrator of the Drug Enforcement Administration is issuing this notice of intent to issue a temporary order to schedule the synthetic opioid, N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide (4-fluoroisobutyryl fentanyl or para-fluoroisobutyryl fentanyl), into Schedule I pursuant to the … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of proposed rulemaking. SUMMARY: The Drug Enforcement Administration (DEA) is proposing a rule that would expand and enhance the enforcement component of the Diversion Control Program (DCP) as previously outlined in the December 30, 1996, Federal Register document … [read more]

Start Preamble Start Printed Page 8593 AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of proposed rulemaking. SUMMARY: The Drug Enforcement Administration proposes placing N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1 H-indazole-3-carboxamide (AB-CHMINACA), N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1 H-indazole-3-carboxamide (AB-PINACA) and [1-(5-fluoropentyl)-1 H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201), including their salts, isomers, and salts of isomers whenever the existence of such salts, … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of intent. SUMMARY: The Administrator of the Drug Enforcement Administration is issuing this notice of intent to temporarily schedule six synthetic cannabinoids: Methyl 2-(1-(5-fluoropentyl)-1 H-indazole-3-carboxamido)-3,3-dimethylbutanoate [5F-ADB; 5F-MDMB-PINACA]; methyl 2-(1-(5-fluoropentyl)-1 H-indazole-3-carboxamido)-3-methylbutanoate [5F-AMB]; N-(adamantan-1-yl)-1-(5-fluoropentyl)-1 H-indazole-3-carboxamide [5F-APINACA, 5F-AKB48]; N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1 H-indazole-3-carboxamide [ADB-FUBINACA]; … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of proposed rulemaking. SUMMARY: The Drug Enforcement Administration is proposing to designate the chemical alpha-phenylacetoacetonitrile (APAAN) and its salts, optical isomers, and salts of optical isomers, as a list I chemical under the Controlled Substances Act. APAAN is … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Withdrawal of Notice of Intent; Solicitation of Comments. SUMMARY: On August 31, 2016, the Drug Enforcement Administration (DEA) published in the Federal Register a notice of intent to temporarily place mitragynine and 7-hydroxymitragynine, which are the main psychoactive constituents … [read more]

Start Preamble AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of intent. SUMMARY: The Administrator of the Drug Enforcement Administration is issuing this notice of intent to temporarily schedule the synthetic opioid, N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-2-carboxamide (furanyl fentanyl), into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances … [read more]

Start Preamble Start Printed Page 63576 AGENCY: Drug Enforcement Administration, Department of Justice. ACTION: Notice of proposed rulemaking. SUMMARY: The Drug Enforcement Administration is proposing to update its regulations for the import and export of tableting and encapsulating machines, controlled substances, and listed chemicals, and its regulations relating to … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background U-47700 Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, Risk There Is to the Public Health Finding of Necessity … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background Mitragynine and 7-hydroxymitragynine, the Main Active Constituents of the Plant Kratom Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Preliminary Note Regarding Treaty Considerations Preliminary Note Regarding Treaty Considerations Basis for the Recommendation for Maintaining Marijuana in Schedule I of the Controlled Substances Act 1. Its Actual or Relative Potential for Abuse 2. Scientific … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Preliminary Note Regarding Treaty Considerations Basis for the Recommendation for Maintaining Marijuana in Schedule I of the Controlled Substances Act 1. Its Actual or Relative Potential for Abuse 2. Scientific Evidence of Its Pharmacological Effects, … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background Butyryl Fentanyl and Beta-Hydroxythiofentanyl Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, Risk There Is to the Public Health … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Legal Authority Background Regulatory Analyses Correction Footnotes Tables Back to Top   DATES: Back to Top Interested persons may file written comments on this correction to the initial proposal in … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing or Waiver of Participation in a Hearing Legal Authority Background Proposed Determination To Schedule 4-MEC, 4-MePPP, α-PVP, Butylone, Pentedrone, Pentylone, 4-FMC, 3-FMC, Naphyrone, and α-PBP Proposed Determination … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, or Waiver of Participation in Hearing Legal Authority Background Proposed Determination To Schedule PB-22, 5F-PB-22, AB-FUBINACA, and ADB-PINACA Proposed Determination of Appropriate Schedule Requirements for Handling PB-22, … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, Notice of Appearance at Hearing, Waiver of an Opportunity for a Hearing or To Participate in a Hearing Legal Authority Background Proposed Determination to Schedule 25I-NBOMe, 25C-NBOMe, … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background MAB-CHMINACA Synthetic Cannabinoids Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, Risk There Is to the Public Health Finding … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, Notice of Appearance at Hearing, Waiver of an Opportunity for a Hearing or To Participate in a Hearing Legal Authority Background Proposed Determination To Schedule Eluxadoline Pre-Clinical … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, Notice of Appearance at or Waiver of Participation in Hearing Legal Authority Background Proposed Determination To Decontrol [123I]Ioflupane 1. The Drug's Actual or Relative Potential for Abuse … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background Acetyl Fentanyl Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, Risk There Is to the Public Health Finding of … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, Notice of Appearance at Hearing, Waiver of an Opportunity for a Hearing or To Participate in a Hearing Legal Authority Background Proposed Determination to Schedule UR-144, XLR11, … [read more]

  Table of Contents Back to Top DATES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Legal Authority Background Synthetic Cannabinoids Factor 4. History and Current Pattern of Abuse Factor 5. Scope, Duration and Significance of Abuse Factor 6. What, if Any, Risk There Is to the Public Health Finding of … [read more]

  Table of Contents Back to Top DATES: ADDRESSES: FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: Posting of Public Comments Request for Hearing, Notice of Appearance at or Waiver of Participation in Hearing Legal Authority Background Proposed Determination To Decontrol Naloxegol 1. The Drug's Actual or Relative Potential for Abuse … [read more]

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